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Choudhary and colleagues thus identified a pair of small molecules that could efficiently penetrate cells and efficiently and reversibly inhibit Cas9’s ability to cut genomic DNA without noticeable toxic effects. “It’s exciting to see this small molecule activity,” says Maxwell. “It’s certainly a whole new way of blocking CRISPR Cas9 activity.” These represent the first […]

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The toxic algae bloomed because there was rarely adequate amounts of water permitted to flow through the weirs upstream. The algae made the fish inedible, which meant fishing was now pointless. The toxic water also meant there was no more swimming, which used to occupy the community youth. Do not store the fruit in temperatures […]